Liver fibrosis leads to abnormal coagulation. It is related to liver insufficiency on one hand and hypersplenism on the other.
1. Liver insufficiency: liver fibrosis can lead to liver insufficiency. Liver insufficiency affects the synthesis of coagulation factors. Reduced synthesis of coagulation factors in the body leads to coagulation disorders.
2. Hypersplenism: Liver fibrosis may also lead to portal hypertension. Portal hypertension leads to splenic stasis, which in turn leads to splenomegaly. In patients with splenomegaly, hypersplenism destroys platelets, which in turn affects coagulation.
Patients with hepatic fibrosis must pay attention to regular coagulation function examination, if necessary, intravenous plasma input, need to actively treat the primary disease.