Pepsinogen 1 and 2 are both much higher, as well as Helicobacter pylori is not necessarily cancer, they are not equivalent. Pepsinogen is an important indicator of people at risk for gastric cancer, and serum pepsinogen is commonly used to screen for gastric cancer. Pepsinogen 1 and 2 are both much higher, as well as Helicobacter pylori is not only related to gastric cancer, but also related to other gastrointestinal diseases, such as acute and chronic gastroenteritis, duodenitis, gastric ulcers, duodenal ulcers and so on. Pepsinogen 1 and 2 are much higher, as well as patients with Helicobacter pylori should be actively screened, improve the electronic gastroscopy and tissue biopsy, tumor markers, gastrin 17, etc. to further clarify the condition, and under the guidance of the doctor to choose the appropriate treatment and medication.