Nifedipine belongs to the calcium channel blocker class of antihypertensive drugs, which can be taken together with diuretics, angiotensin-converting enzyme inhibitors or angiotensin receptor blockers. 1, diuretics: representative of the drug hydrochlorothiazide, smooth onset of action, 2 to 3 weeks to reach the peak, can discharge sodium, reduce extracellular volume, reduce peripheral resistance. 2, angiotensin converting enzyme inhibitors: representative drug captopril, slow antihypertensive, 3 ~ 4 weeks to reach the maximum antihypertensive effect. 3、Angiotensin receptor blocker: representative of the drug chlorosartan, slow antihypertensive, usually in 6 to 8 weeks to reach the maximum antihypertensive effect. The above three types of drugs can be combined with nifedipine to achieve the purpose of lowering blood pressure. The use of drugs should be under the guidance of a professional physician, do not take medication on your own, so as not to cause adverse consequences.