Lung nodule measuring 16mmx15mm with burr is considered to have a high probability of malignant nodule, which can be treated with puncture biopsy or surgical resection, postoperative pathologic examination, and further treatment based on the pathologic findings. Lung nodule is a small lung mass detected by chest imaging, which can be categorized into benign and malignant nodules. Characteristics of benign nodules include clear margins, uniform density, no lobulation inside the nodule, and no burrs. Malignant nodules are characterized by blurred margins, uneven density, lobulation, burrs or vascular shadows. According to China’s lung nodule classification and treatment guideline, for 16mmx15mm lung nodules with nodules having burrs, which are high-risk nodules for lung cancer, further refinement of lung puncture biopsy can be made under doctor’s guidance to clarify the nature of the nodule, or direct surgical resection can also be performed, and postoperative refinement of pathology examination may be needed according to the pathological results of the subsequent radiotherapy, chemotherapy, and so on. If you find lung nodules, it is recommended that you consult a doctor in a timely manner, under the guidance of a professional doctor, to clarify the diagnosis and standardize the treatment.