The therapeutic effect between Clarithromycin and Furazolidone should be determined according to the results of the patient’s drug sensitivity and the actual condition of the patient, the relevant patients, if necessary, can also be used in combination with these two drugs to obtain better therapeutic effect. Clarithromycin is a kind of macrolide antibiotic drug, has antibacterial effect on gram-positive bacteria and some gram-negative bacteria, can treat infectious diseases caused by sensitive pathogens. Furazolidone is a nitrofuran antibacterial drug, which has antibacterial effect on gram-positive bacteria as well as gram-negative bacteria, and can treat enteritis, bacillary dysentery, cholera, paratyphoid fever, trichomoniasis and so on caused by sensitive bacteria. There is a lot of overlap in the antimicrobial spectrum between clarithromycin and furazolidone, and the two drugs can be used in combination to treat related conditions, so there is no question of which drug is more effective. In terms of adverse reactions, those caused by clarithromycin mainly include bad taste in the mouth, abdominal pain, nausea, diarrhea, vomiting, headache and so on. The main adverse reactions caused by furazolidone include nausea, vomiting, dizziness, headache, rash, anal itching, drug fever, and hypoglycemia. In terms of contraindications, both with clarithromycin and furazolidone, those who are allergic to the ingredients contained in the drug need to be contraindicated. Also furazolidone needs to be contraindicated in people with glucose 6 phosphate dehydrogenase deficiency. Clarithromycin is contraindicated in pregnant women, lactating women, people with water-electrolyte disorders, and people with severe hepatic impairment. As for precautions, during the treatment with furazolidone, the intake of alcohol is prohibited within five days of stopping the drug. Whether you are using Clarithromycin or Furazolidone, you should follow the doctor’s instructions to standardize the use of medication.