How long it takes for chronic lymphatic leukemia to develop from the onset of the disease is not always possible, sometimes it can take several years, and in the long run, it can take a lifetime without clinical symptoms. Chronic lymphocytic leukemia is usually a clonal proliferative malignancy of mature B lymphocytes, usually characterized by the accumulation of mature lymphocytes in the body, resulting in a gradual increase in the number of lymphocytes in the blood and bone marrow, and the development of enlarged lymph nodes, liver, and spleen, and eventually the involvement of other tissues. Chronic lymphatic leukemia is a very insidious disease, often not easy to detect in the early stage, patients may have some non-specific symptoms, such as fatigue, weakness and so on. With the gradual progression of the disease, patients may develop severe anemia, recurrent infections, fever, and even bleeding tendency, and some patients may have enlarged lymph nodes in the liver and spleen, which need to be treated under the guidance of a physician in a timely manner.