Sore throat caused by staying up all night is mostly a localized inflammation caused by viral or bacterial infection of the throat, such as acute pharyngitis, acute tonsillitis, acute laryngitis, and so on. The drugs that may be involved are anti-viral drugs, anti-bacterial drugs, etc. Please follow the doctor’s instructions for medication. 1. Antiviral drugs: patients with pharyngitis, tonsillitis and laryngitis caused by viral infections can use antiviral drugs such as morpholino, amantadine and interferon as prescribed by the doctor. 2. Antibacterial drugs: patients with pharyngitis and laryngitis caused by bacterial infections can choose antibiotics, such as cephalosporins and penicillin antibiotics, etc. Penicillin antibiotics are preferred for tonsillitis patients. In addition, you can use iodine tablets, silver yellow tablets, mint throat tablets and other tablets to reduce inflammation and pain; you can also use compound borax solution, furacilin solution, compound chlorhexidine gargle and other gargles. In addition to the above factors, other factors can not be ruled out. It is recommended that patients consult a doctor in a timely manner to clarify the cause of the disease, and then give targeted treatment, do not blindly self-medication.