Hand eczema can not be cured at present, the course of the disease is prolonged, easy to recur, but can be through the regular treatment to improve the symptoms and control the condition. Hand eczema is mainly caused by a variety of internal and external factors caused by the hand skin inflammatory reaction, the etiology is unknown, may be related to long-term contact with irritating substances, such as acids, alkalis, organic solvents, soaps, latex, etc., or mechanical injury and other factors. It is characterized by flaky erythema, papules, blisters, hyperkeratosis, scaling, and obvious itching on the hands, which are stubborn and difficult to treat and are prone to recurrence. After the diagnosis of hand eczema, you can use topical glucocorticoid treatment under the guidance of the doctor, such as mometasone furoate, halometasone cream, etc.; calcium-modulated phosphatase inhibitor treatment, such as tacrolimus ointment, pimecrolimus cream, etc.. When the itching is more serious, oral antihistamine treatment, such as loratadine, cetirizine and so on. However, the cause of hand eczema is unknown and cannot be cured. It is recommended that patients usually do a good job of hand skin care, pay attention to hand moisturizing, avoid direct contact with irritating substances, wear good protective gloves when necessary, to prevent eczema recurrence.