Biologics are usually effective in treating rheumatoid arthritis, but there are individual differences. Most of the biologics are targeting cytokines or receptors of cytokines for targeted therapy, which can significantly relieve the symptoms of rheumatoid arthritis morning stiffness, joint swelling, joint pain, and can play a role in protecting the joints in the long-term treatment. Often the use of biologics treatment is effective, but there are individual differences, different people have different efficacy. Commonly used biologics for rheumatoid arthritis include etanercept, adalimumab, infliximab, tolizumab, tofacitib, etc. Different biologics have different mechanisms of action and methods of use, and the specific type of biologics that is suitable for you needs to be selected under the judgment of the treating doctor. It should be noted that biologics are not suitable for all patients with rheumatoid arthritis, before starting to use them, they need to do a physical assessment under the guidance of a doctor, and their use is generally not recommended for patients with serious infections or tuberculosis. It is recommended that patients go to the hospital in a timely manner and use biologics under the guidance of a doctor.