Clomipramine can reach the peak concentration of the drug after a few hours, so as to exert the effect of the drug. Clomipramine belongs to the tricyclic antidepressant drugs, after the use of the central nervous system can block the reuptake of norepinephrine and pentetrahydroxytryptamine, can play an antidepressant and anti-anxiety effect, but also has a sedative and anticholinergic effect, mainly used in the treatment of obsessive-compulsive neurosis, phobic neurosis and other diseases. Usually, the drug is fully absorbed orally and reaches its peak concentration within a few hours to show its effect. It can maintain its concentration in the body for about 22-84 hours, and finally it will be metabolized by the liver and excreted from the body through the urine. Secondly, the drug may cause excessive sweating, dizziness, drowsiness and other discomforts after taking it. It is contraindicated for people with severe heart disease, glaucoma, allergy to the components of the drug. During the administration of the drug it is necessary to monitor the functions of the liver and kidneys, and it is not advisable to drive a vehicle. Since the drug is secreted into breast milk, breastfeeding women need to use it under medical supervision. If you need to use the drug, it is recommended to use the drug under the guidance of a doctor, do not blindly self-medication, in order to avoid adverse effects.