Swelling caused by thyroid disease may be due to hypothyroidism or Graves’ disease, which should be actively treated for the primary disease, and at the same time, symptomatic treatment can be taken to reduce swelling. 1. Hypothyroidism: hypothyroid patients have low metabolism, protein accumulation under the skin, mucous edema, need to follow the doctor’s prescription of thyroid hormone supplementation therapy, to control the thyroid hormone within the normal range. 2. Graves’ disease: heart failure, anterior tibial mucous edema and other conditions may cause edema, should follow the doctor’s advice to use antithyroid drugs, radioactive iodine or surgical treatment of the primary disease. If it is caused by heart failure, use cardiotonic diuretics at the same time to control the symptoms of heart failure in order to relieve edema. Patients with thyroid disease who develop edema should seek prompt medical attention.