If patients with coronary heart disease have symptoms of swollen legs after taking medication, it is necessary to identify the cause, control the original disease, and take medication for relief if necessary. Coronary heart disease patients with swollen legs, must promptly seek medical attention, go to the hospital to clarify the cause of swollen legs, and actively carry out relevant examinations. To see whether and heart abnormalities related to whether coronary heart disease caused by heart failure and triggered by the swelling of the legs. Heart failure, for the cause of treatment, such as aspirin, atorvastatin, isosorbide mononitrate treatment, to improve cardiac function blood, at the same time serving furosemide, spironolactone and other diuretics to correct heart failure, note that if you are taking diuretics, to carry out potassium monitoring, so as not to cause electrolyte disorders. Sometimes leg swelling may be an adverse drug reaction, such as coronary heart disease combined with hypertension, taking nifedipine may cause lower limb edema. Or when patients with coronary heart disease take drugs such as captopril to improve myocardial remodeling treatment, there may also be swelling of the lower extremities and other vasogenic edema manifestations. Adjust the medication if necessary after a thorough evaluation of the etiology by a physician. Symptoms should be promptly seek medical attention, under the arrangement of the doctor to use drugs, self-medication is not recommended.