Crohn’s disease may have complications such as intestinal obstruction and is difficult to treat completely, but it can be managed through evaluation and stratified treatment. Therefore, there is no such thing as “horror”, so please cooperate with your doctor for active treatment. Crohn’s disease, the cause of which is unknown, is a chronic inflammatory granulomatous disease of the intestinal tract that can occur in any part of the digestive tract and is characterized by abdominal pain, diarrhea, and abdominal masses. Treatment mainly includes the use of medication such as mesalazine, salazosulfapyridine, prednisone, and biologics. Surgery should be considered when complications such as intestinal obstruction occur. Crohn’s disease cannot be completely cured, patients with long-term diarrhea, abdominal pain and other symptoms can seriously affect the daily life, even if the surgical treatment still have a tendency to relapse, recurrence of intestinal obstruction, acute perforation and other complications. However, it can be controlled through evaluation and stratified treatment. Patients diagnosed with Crohn’s disease should actively cooperate with their doctors in treatment and maintain a healthy lifestyle and optimistic mindset, which also helps to improve the prognosis.