The sensation of pins and needles like stinging pain on the sole of the foot like ants’ bites may be the cause of polyneuritis, acute myelitis, etc., which can be intervened by medication and physical therapy. 1. Polyneuritis: there may be numbness in the limbs, abnormal pin-prick pain or burning pain; it can be treated with immunomodulating drugs (such as glucocorticoids, immunoglobulins, etc.), neurotrophic drugs (such as gangliosides, etc.), and neuralgia-blocking drugs (such as carbamazepine, etc.), and other drugs. 2. Acute myelitis: The symptoms of sensory abnormalities are similar to those of polyneuritis, but they are also accompanied by motor abnormalities, limb paralysis, and bowel and bladder abnormalities or disorders. It can be treated with glucocorticoid drugs, immunoglobulin, nutritive nerve drugs, etc. Patients with serious conditions may also be combined with life-threatening respiratory muscle paralysis, etc. It is recommended to standardize the treatment under the guidance of a doctor. The symptoms like ant bites on the foot plate may also be caused by other diseases, it is recommended that patients with this symptom go to the regular hospital for a clear diagnosis in a timely manner, under the guidance of the physician to use medication, prohibit unauthorized use of medication.