Chronic sinusitis for more than ten years through standardized treatment, most patients can achieve clinical cure. The main drug treatment (such as isoprinosine hydrochloride, benzylamine hydrochloride, clarithromycin), surgical treatment (nasal endoscopic surgery), etc. 1. drug treatment: patients with chronic sinusitis in the acute stage can use antibiotics such as cefuroxime, amoxicillin clavulanic acid potassium and so on. Accompanied by allergic rhinitis, asthma patients can be applied to anti-allergic drugs, such as isoprinosine hydrochloride, phenylephrine hydrochloride and so on. Glucocorticoid drugs can also be applied, such as mometasone furoate, budesonide nasal spray. 2. Surgery: Patients with chronic sinusitis who are not treated with medication usually need endoscopic surgery, and most of them can be clinically cured. It is recommended that patients with chronic sinusitis go to the hospital in time for relevant examinations and standardized medication and treatment.