Perindopril and Lenopril are not recommended to be taken together, they belong to the same class of drugs and should be used in combination as prescribed by the doctor. Perindopril, commonly available in tablet form, is an angiotensin II receptor antagonist that reduces peripheral vascular resistance, decreases blood pressure, and lowers cardiac load. It can be used for hypertension as well as congestive heart failure. Adverse effects of perindopril can be seen as fatigue, dizziness, headache, painful cramps, mood or sleep disturbances, hypotension, stomach pain, nausea, rash, anorexia, and taste disturbances. The drug is contraindicated in people who are allergic to the product, fourth to ninth month of pregnancy, etc. Lenopril also belongs to a kind of angiotensin II receptor antagonist, which causes peripheral vasodilatation and decreases vascular resistance, causing a hypotensive effect. It is used in the treatment of essential hypertension. Adverse effects of this product include dizziness, headache, cough, palpitations, and fatigue. The drug is contraindicated in those who are allergic to the product, those who have bilateral renal artery stenosis, hyperkalemia, and pregnancy. Perindopril tert-butylamine salt tablets and Lenopril belong to the same type of antihypertensive drugs, antihypertensive mechanism is similar, the same use can cause low blood pressure, so it is not recommended to use at the same time. Therefore, it is not recommended to use them at the same time. They should be used reasonably under the guidance of a doctor.