Is immunohistochemical testing required for focal epithelial considerations of heterogeneous hyperplasia of the uterine cervix?



Instead of immunohistochemistry, interferon antiviral therapy should be administered, and cervical biopsy and review should be performed regularly.

The presence of heterogeneous hyperplasia in the focal epithelium of the cervix indicates that the cervix has localized precancerous lesions, which can be treated with anticancer therapies, aiming at effectively controlling the proliferation of cancerous cells and tissues, and decreasing the incidence of other gynecological cancers, such as cervical cancer. Since cervical cancer itself progresses slowly, early cancer prevention and interferon antiviral therapy can effectively control the progression of cancer and prevent deterioration.

Immunohistochemical testing is generally used for differential diagnosis of complex cancers. Immunohistochemistry can further diagnose the nature of the tumor, its growth rate or potential direction of development, thus helping to determine the benign and malignant tumors, as well as assisting in making treatment plans. Immunohistochemistry is therefore generally indicated for conditions where the nature of the tumor cannot be directly determined or where complex tumors are present.

Cervical biopsies should be performed regularly after HPV infection to follow up on HPV infection status and cervical health.