Monoclonal gammopathies are not rare diseases, but the incidence is not very high.
Monoclonal gammaglobulinopathies are a large group of diseases, including multiple myeloma, Hutchinson’s macroglobulinemia, systemic amyloidosis, and many other diseases, which belong to the malignant diseases of the blood system, and these diseases have a common feature of abnormally elevated monoclonal immunoglobulin.
Patients with monoclonal gammaglobulin disease have decreased autoimmunity and may have recurrent bacterial, viral, and tuberculosis infections, etc., and the monoclonal immunoglobulin may be deposited in the renal tubules and lead to renal function impairment and other complications.
It is recommended that patients with monoclonal gammaglobulin disease should go to the hematology department in time for further improvement of bone marrow aspiration and biopsy, immune protein electrophoresis, serum protein electrophoresis, serum and urine free light chain tests to further clarify the diagnosis, and then carry out targeted treatment for specific diseases.