There are many reactions to menopause, commonly including hot flashes, sweating, insomnia, palpitations, dizziness, headache, tinnitus, significant mood swings such as irritability, restlessness, low mood, depression, and even inability to self-control emotions, and strained relationships with family members as well as friends. In the long term, there will be some complications, such as urogenital atrophy and difficulty in sexual intercourse. In the more distant stages, osteoporosis may manifest itself, and dementia, a condition associated with Alzheimer’s disease, may also occur. Depending on the patient’s condition, and in the absence of obvious contraindications, it is advisable to give the appropriate hormone replacement therapy to alleviate the obvious discomfort associated with the above. Hormone replacement therapy should be considered only after appropriate investigations have been performed, such as screening for breast-related diseases and for the presence of obvious fibroids.