Acne with yellow pus on the face may be folliculitis or secondary infection of acne, which can be regulated by general treatment, medication, surgery and other measures. 1. General treatment: keep the skin clean and hygienic, avoid squeezing, avoid scratching, and choose light, soft, easily absorbed and digested food for your diet. 2. Medication: Folliculitis can be treated with antibiotic drugs such as erythromycin ointment, metronidazole gel, mupirocin ointment, etc.; after the inflammation subsides; if acne is present, it can be treated with drugs such as adapalene gel, azelaic acid cream, etc., and in severe cases, it is necessary to combine with doxycycline and isotretinoin for treatment. 3. Surgical treatment: if the formation of abscess failed to heal itself, more pus can be considered incision and drainage, regular dressing change and other surgical measures. Acne on the face with yellow pus should be timely medical treatment, all drugs need to be used under the guidance of a professional doctor.