There is a possibility of long-term survival with tumor in advanced stage of gastric cancer, and the prognosis can be improved by systemic chemotherapy, stent implantation, etc., or nutritional support therapy such as amino acid can be given to prolong the survival period. In the advanced stage of gastric cancer, radical treatment cannot be achieved, but the prognosis can be improved through reasonable individualized treatment. Although the chance of radical treatment by surgery is lost, systemic chemotherapy treatment can be carried out, which can temporarily control the progression of the tumor and prolong the survival period to a certain extent. If patients with advanced gastric cancer meet the indication of stent implantation, stent implantation can solve the supportive measures of feeding or nutrition and improve the prognosis of patients. If patients with advanced gastric cancer have poor general status and cannot tolerate systemic chemotherapy treatment, they can be treated with nutritional support symptomatic treatment, such as amino acid, fat milk and other nutritional supportive treatments, to improve the survival period and prolong life as much as possible. Whether advanced gastric cancer can survive with tumor for a long time or not requires timely consultation in hospital for clear diagnosis and treatment to improve the prognosis.