Knuckle pain on taking Atorvastatin Calcium Tablets is considered to be an adverse drug reaction leading to knuckle pain, and different treatments need to be given depending on the level of pain and the level of creatine kinase. The main adverse reactions to taking atorvastatin calcium tablets are: 1.Adverse reactions are gastrointestinal discomfort, others are headache, rash, dizziness, blurred vision and taste disturbances. null2.Occasionally, it can cause reversible elevation of blood aminotransferase. Therefore, liver function needs to be monitored. null3.Rare adverse reactions include impotence and insomnia. null4.Rare adverse reactions include myositis, myalgia, and rhabdomyolysis, which are manifested as muscle pain, fatigue, and fever, accompanied by elevated blood creatine phosphokinase and myoglobinuria. null5.Rhabdomyolysis can lead to renal failure, but it is rare. null6.Rhabdomyolysis can lead to renal failure. null7.Rhabdomyolysis can lead to renal failure. null8.Rhabdomyolysis can lead to renal failure. null9. To eat atorvastatin calcium tablets appear knuckle pain suggestions: 1. If the symptoms of the knuckles are mild, creatine kinase is normal or mildly elevated, appropriately reduce the dosage or change the drug under the guidance of the doctor, and regularly review the creatine kinase level. 2. If the symptoms of the knuckles are more serious and gradually aggravated, creatine kinase level rises more than 10 times, liver and kidney functions are abnormal, and even myoglobinuria occurs, it is recommended to stop taking the drug immediately, and give sodium bicarbonate and other drugs to alkalize the urine and other treatments in a timely manner. Therefore, when taking atorvastatin calcium tablets with symptoms such as knuckle pain, it is recommended that the patient consult a doctor in time for the next step in the treatment under the guidance of the doctor.