Traditional Chinese medicine is not effective in treating poorly differentiated gastric adenocarcinoma, and it is mostly used as auxiliary treatment to improve patients’ discomfort. Low-fractionated gastric adenocarcinoma has a higher degree of malignancy, rapid development of its condition, and is relatively more difficult to treat. It needs to be treated in accordance with the staging and mainly focuses on surgery, radiotherapy, chemotherapy and targeted therapy, while some patients can be treated with traditional Chinese medicine. Some patients can be treated with traditional Chinese medicine. Traditional Chinese medicine can be used according to the symptoms of patients, but it is mostly used as an auxiliary treatment to improve the discomfort of patients and enhance the overall immunity, which is helpful to the recovery of the disease, but it has limited effect on the gastric adenocarcinoma itself. If patients have hiccups, vomiting, weakness, emaciation, poor appetite after chemotherapy or radiotherapy, they can use traditional Chinese medicine under the guidance of doctors to relieve the side effects of treatment. Traditional Chinese medicine can be used in the treatment of gastric adenocarcinoma, but it cannot be used as a mainstream method and must be guided by professional doctors.