For esophageal reflux does not have the claim of effective drugs, commonly used in the treatment of drugs to inhibit gastric acid, such as ranitidine, rabeprazole, etc.; to promote gastric power of drugs such as mosapride; gastric mucosal protective agents such as magnesium aluminum carbonate, bismuth potassium citrate, etc.. Esophageal reflux mainly refers to the reflux of gastric contents into the esophagus causing discomfort, so you can use drugs to inhibit gastric acid to relieve. Commonly used in clinical practice are proton pump inhibitors, such as omeprazole, rabeprazole, etc.; there are also H2 receptor antagonists, which have relatively weak effects, such as ranitidine, cimetidine, etc. Some patients with esophageal reflux can be combined with gastric emptying obstruction, gastric tolerance is impaired, at this time can be added with pro-dynamic drugs, such as domperidone, mosapride, itopride, etc. as a complementary acid-suppressing drugs. Mucosal protectants, including magnesium aluminum carbonate and aluminum thioglycollate, can also be given to patients, and such drugs are only suitable for temporary relief of symptoms in patients with mild symptoms and intermittent episodes. Patients with esophageal reflux are advised to use medications under the guidance of a physician and to make lifestyle changes to control weight, quit smoking and drinking, and avoid eating before bedtime.