Female patients with fever in the heart of hands and feet may belong to the Yin deficiency fever type of internal injury fever according to Chinese medicine’s diagnosis and treatment, and may choose to take Bone Clearing Powder. If the patient manifests fever in the heart of hands and feet, fever at night, or hot flashes in the afternoon (a burst of fever), irritability, dry throat and mouth, night sweating (abnormal sweating after going to sleep, but the sweating stops after waking up), and hypersomnia and excessive dreaming, etc., according to Chinese medicine’s diagnosis and treatment, it belongs to the yin-deficiency fever type, so it may be treated by taking Bone-cleansing Powder with additions and subtractions. Bone-clearing powder consists of Chai Hu, Hu Huang Lian, Gentiana Macrophyllae, Phellodendron Bidentatae, Bone Skin of the Earth, Glycyrrhiza Glabra, Artemisia Annua and Zhi Mu. Its efficacy is for clearing the heat of yin deficiency and relieving the bone vapor, and it is mainly used for treating the symptoms of bone vapor and tidal fever (a burst of heat, feeling that the heat comes from inside the bone to the outside) or low fever that does not go away for a long period of time, fever of the palms and feet and heart, and drowsiness and night sweating. The adverse effects of Bone Clearing San are not clear, and it is not suitable for patients with more Yin deficiency and milder hot flashes. If the patient has symptoms of fever in the hands and feet, it is recommended to go to a regular medical institution, not self-medication, so as not to delay the condition.