Infection of nails and their surrounding tissues with Pseudomonas aeruginosa can be intervened by systemic anti-infective drug therapy, local drug therapy, and debridement and drainage. 1. Systemic anti-infective drug treatment: If symptoms such as fever occur and Pseudomonas aeruginosa infection is confirmed by bacterial culture, anti-infective drugs such as ticarcillin, piperacillin, gentamicin can be used for treatment, and if the above drugs are not effective in the treatment, they can be replaced with drugs such as ceftazidime and imipenem. 2. Local medication: while systemic medication is carried out, iodophor, potassium permanganate solution and other medications can be used locally for local application or wet compresses. 3. Drainage: For those with local abscess formation, incision and drainage can be carried out to promote the drainage of pus and facilitate infection control. If you have the above symptoms or suspect that you are infected with Pseudomonas aeruginosa, it is recommended that you go to the hospital in time to see a doctor who can check the infected foci, assess the severity of the disease and decide on the treatment plan, and do not make any judgment on your own, so as to avoid delaying the treatment and worsening the condition, and the infection spreads to the fingers or palms of the hand; the above medications need to be used under the guidance of the clinician.