Neural tube defects can usually be detected on a labor and delivery test. Neural tube defects are a serious malformation disorder that can lead to severe birth defects in the fetus, mainly including anencephaly and spina bifida. Pregnant women can detect the presence of neural tube defects through labor and delivery tests, such as methotrexate and ultrasound. Pregnant women can have their blood collected to test for alpha-fetoprotein. If the alpha-fetoprotein in a pregnant woman’s body is abnormally elevated, this is a sign that the fetus may have an abnormality and be at a higher risk for neural tube defects. Pregnant women can be screened for neural tube defects during labor and delivery by ultrasound. The ultrasound examination can carefully observe the fetal spinal pattern and the structure of the nervous system, and this examination can well determine whether there are neural tube defects. Therefore, pregnant women need to go to the hospital regularly for maternity checkups, so that they can promptly detect any problems that occur during the development of the fetus.