Mucus with blood in the stool needs to be clarified after the cause is clear, and then consider whether the drug treatment and medication program. Physiological reasons such as less exercise and less water intake usually do not require medication. For pathological reasons such as acute enteritis, dyspepsia and hemorrhoids, commonly used medications include norfloxacin, bifidobacterium tetraprolium tablets and diosmin. 1. Physiological causes and treatment: such as less exercise, less water can lead to dry stools, defecation can be caused by perianal blood vessel rupture bleeding, stool with mucus symptoms, generally no treatment, through dietary adjustments, active exercise, drink more water and so on can be restored to normal. 2. Pathological causes and treatment: acute enteritis can be used as prescribed by the doctor, such as norfloxacin, levofloxacin and other drugs; dyspepsia can be used bifidobacterium tetraprolium tablets, lactobacillus and other drugs; hemorrhoids can be orally dioxymethamphetamine, potassium permanganate sitz bath and so on. It is recommended that patients with blood in the stool mucus go to the hospital in time, to clarify the cause, and active treatment. Drugs need to be used under the guidance of a doctor.