Itching in the lower part of the 35th week of pregnancy may be caused by vaginitis, non-specific vulvovaginitis, intrahepatic cholestasis in pregnancy and other reasons. 1. Vaginitis: when pregnancy combined with vaginal inflammation will cause vulvar itching, such as trichomonas vaginitis, vulvovaginal pseudomycosis, etc., may also be accompanied by increased vaginal discharge, can be combined with the clinical manifestations, the nature of the secretion and vaginal secretion routine examination to clarify the diagnosis, and comply with the doctor’s instructions to actively treat. 2. Non-specific vaginitis: caused by wearing chemical fiber underwear for a long time and not paying attention to personal hygiene, etc. It may also manifest as vulvar itching, and vulvar congestion and swelling can be seen on examination, which can be diagnosed by combining with the medical history and clinical manifestations. 3. Intrahepatic cholestasis in pregnancy: mostly occurring in late pregnancy, mainly manifested as itching without skin damage, mostly starting at the end of the limbs, and then gradually extended to the proximal limbs, can also cause vulvar itching, can be combined with the history and serum bile acids, liver function measurements, etc. can help diagnosis. When 35 weeks pregnant below the itch is recommended to go to the hospital in time to identify the cause, and active treatment.