High platelets and low hemoglobin means that the number of platelets in the peripheral blood exceeds the normal range, but the hemoglobin concentration is reduced. There are various reasons for this condition: i. In patients with iron deficiency anemia who have recently had an infection, such as an upper respiratory tract infection, the number of platelets increases reactively due to the stimulation of infectious factors. But at the same time, there is anemia itself, and when doing routine blood tests, there is an increase in the number of platelets, but a decrease in the concentration of hemoglobin. Second, patients with trauma, after trauma due to massive bleeding, resulting in lower hemoglobin, and at the same time, due to trauma or surgery, will cause a reactive increase in the number of platelets, also appear to increase the number of platelets, but lower hemoglobin. Third, after chemotherapy, patients with leukemia reach myelosuppression, and after myelosuppression begins to remit, the number of platelets will appear a kind of rebound increase, that is, the number of platelets will exceed the normal range, but the growth rate of red blood cells is slow, at this time there will still be anemia.