There is no clinical subtype of follicular vitiligo, and the disease is categorized into 4 types, segmental, non-segmental, mixed and undefined, according to the extent and distribution of the lesions. The cause of vitiligo is not particularly clear, and is considered to be related to immune factors, oxidative stress, and neurochemical factors. 1. immune factors: the pathogenesis of vitiligo may be related to immune factors, 40% to 80% of patients in the serum of the patient’s serum in the presence of anti-melanocyte antigen autoantibodies, in the active phase of the disease and family history of patients with a positive positive antibody rate is higher. Some patients with vitiligo are also associated with autoimmune diseases. 2. oxidative stress: vitiligo lesion area redox imbalance, through the lesion area peroxidase and other antioxidant enzyme level reduction, affecting melanocyte metabolism, proliferation and differentiation, causing mitochondrial function abnormalities and apoptosis, damage to melanocytes. 3. neurochemical factors: part of the vitiligo damage is distributed along the ganglion, may be the melanocytes around the neurochemical transmitter catecholamines increase melanin synthesis is impeded. The cause of vitiligo is not clear, currently considered and immune factors, oxidative stress, neurochemical factors and so on. It is recommended that the patient to the hospital in time to consult the examination, with the doctor’s treatment.