Thrombocytopenia in acute leukemia patients is due to abnormal proliferation of leukemia cells and inhibition of normal red blood cell and platelet proliferation. The common leukemias are acute lymphoblastic leukemia and acute granulocytic leukemia, which are mainly manifested by the excessive proliferation of leukemia cells in the bone marrow, while the proliferation of normal cell components such as red blood cells and platelets is inhibited. Therefore, clinical manifestations such as anemia, bleeding, and infection will occur. When the patient has thrombocytopenia, there will be scattered bleeding spots on the skin, and women may have excessive menstruation. Patients with acute leukemia need to be treated with chemotherapy such as cytarabine and cyclophosphamide under the guidance of physicians, and platelet transfusion and hemostatic treatment with aminomethylcholine should be given in a timely manner to actively prevent and control organ hemorrhage.