Clinically, there is no such thing as whether it is better to have large urine volume or small urine volume in membranous nephropathy. Normal urine volume should be 1000~2000ml, but if the patient’s urine volume is less than 400ml per day, it is oliguria, which may indicate renal insufficiency. It is recommended that the patient should consult the doctor in time. Membranous nephropathy is one of the pathological types of nephrotic syndrome, mostly related to immune diseases, but also secondary to infection, drugs and malignant tumors and other factors. Membranous nephropathy can be seen at any age, the onset of insidious, some patients will appear asymptomatic proteinuria, serious cases can produce a large amount of proteinuria, often accompanied by edema and weakness and other symptoms, easy to combine with venous thrombosis. Patients with membranous nephropathy are advised to go to regular hospitals in time and receive standardized treatment under the guidance of doctors.