The main difference between Bifidobacterium Triplex and Bifidobacterium Quadruplex is the different strains and quantities of bacteria, and the therapeutic effects, adverse reactions, contraindications, precautions, etc. of the two drugs are basically the same. Bifidobacterium triplex mainly has three kinds of beneficial bacteria, namely Bifidobacterium bifidum, Enterococcus faecalis and Lactobacillus acidophilus. Bifidobacterium quadruple mainly has the strains of Bifidobacterium infantis, Lactobacillus acidophilus, Enterococcus faecalis and Bacillus cereus. Quadruplex has more strains and numbers of bacteria and generally has a better therapeutic effect. Both drugs can improve intestinal flora and promote the growth of beneficial bacteria, and are used for diarrhea, constipation, and dyspepsia caused by imbalance of gastrointestinal flora. The adverse reactions of the two drugs are not yet clear, and they are contraindicated for those who are allergic to these two drugs. Pregnant women as well as lactating women should use these two drugs under the supervision of a doctor. During the use of these drugs should be avoided together with acid-producing drugs and antibacterial drugs, so as not to reduce the effectiveness of the drug. Both drugs are live bacteria and should be kept away from light and can be taken with cold or warm water. If you need to use these two drugs, you should use them rationally under the guidance of your doctor.