Urinary creatinine 1004.28μmol/24h is low at this time, generally seen in physiological lowering such as drinking a lot of water, long-term vegetarians, etc., at this time is often not serious; can also be seen in pathologic lowering, such as acute kidney injury, chronic renal failure, hyperthyroidism and other diseases, at this time, the condition is more serious, and need to pay attention to. The normal range of urinary creatinine is 7000～18000μmol/24h for adult male and 5300～16000μmol/24h for adult female. 1. Physiologic decrease: Commonly found in cases such as drinking a lot of water and sweating less, long-term vegetarians, etc., generally not serious. 2. Pathological decrease: commonly found in acute kidney injury, chronic renal failure, hyperthyroidism, severe congestive heart failure, myotonic dystrophy, leukemia, anemia and other diseases, the condition is more serious at this time, if not actively regulated by the treatment, the condition can be further progressed, and even life-threatening, it is recommended to seek medical treatment in a timely manner. If you find abnormal urinary creatinine, it is recommended that the patient follow the doctor’s instructions to improve the relevant examination, to clarify the cause of the disease, and then follow the doctor’s instructions to standardize the treatment.