The primary treatment for sca3 cerebellar ataxia is symptomatic supportive therapy, which is almost impossible to cure. Cerebellar ataxia of type sca3 is a type of spinal cerebellar ataxia, which is common in Japan, China, Germany and Portugal. The disease mainly damages brain structures such as the cerebral bridges, the cerebellar tracts of the spinal cord, and the substantia nigra. In addition to symptoms of ataxia, eye movement disorders, proptosis, and peripheral neuropathies are also commonly seen. The disease is a genetic disorder caused by a genetic defect, so there is no good treatment at present. Symptomatic supportive therapy is the main treatment at present, the use of buspirone can improve ataxia symptoms, the use of levodopa can improve the symptoms of myasthenia gravis. Lamotrigine can also improve sca3 gait abnormality. In summary, there is no cure for this disease, but symptomatic supportive treatment can improve symptoms and quality of life. Patients should actively cooperate with the treatment to ensure the quality of life, and patients with childbearing plans should undergo genetic counseling in advance.