There is no clinical method for the natural discharge of kidney stones, and patients need to follow the doctor’s instructions for drug treatment, surgical treatment, and general measures. 1. Drug therapy: usually for patients with renal colic, need to comply with medical advice to use diclofenac, indomethacin and other non-steroidal analgesic and anti-inflammatory drugs, if the symptoms are more serious can also be injected intramuscular pethidine, tramadol and other opioid analgesics or the use of atropine sulfate, scopolamine and other antispasmodic drugs treatment. Patients can also be used with tamsulosin and other alpha-blockers, so that the ureteral smooth muscle relaxation, thereby promoting the discharge of stones. 2. Surgery: patients need to according to their own degree of illness, under the guidance of the doctor for surgical treatment. Generally speaking, if the stone diameter is 6-20mm in the renal pelvis or middle and upper calyces, extracorporeal shock wave lithotripsy can be performed according to the doctor’s instruction. For stones that are difficult to be crushed by extracorporeal shock wave lithotripsy or fail to be treated, percutaneous nephrolithotripsy can be adopted. If the diameter of kidney stone is less than 2cm, ureteroscopic lithotripsy can also be performed. 3. General measures: patients usually need to drink more water, which is conducive to the discharge of small stones or reduce the formation of stones, and patients also need to rationalize the planning of the diet, control sodium, purine, protein intake, and also avoid eating strong tea. It is recommended that patients with kidney stones timely and reasonable treatment under the guidance of a doctor, so as not to delay the condition.