Sequestration generally refers to localized sealing treatment, after which normal work and life can be resumed if there is no serious discomfort. It is also related to the underlying disease and the nature of work. Closure therapy is mainly used for the treatment of tenosynovitis, humeral epicondylitis, fasciitis and other common orthopedic diseases. After treatment, it should be closely observed for any allergic reaction, high fever, etc., and in case of serious complications, medical attention should be sought promptly. If there is no serious discomfort, you can resume normal work and life. Generally, local pain, swelling and numbness of different degrees can occur within 2 to 3 days after the closed treatment, which can disappear on its own. Do not immerse the puncture localization in water for three days, keep the localization clean and dry, and prevent infection around the needle eye. Pay attention to rest, local braking, and avoid excessive activity of the neighboring joints of the closed place. Accompanied by underlying diseases or diseases caused by the nature of work, etc. will affect the effect and recovery time of the closed treatment. Consult your doctor for details.