Esophageal reflux causing chest choking and blockage is usually related to reflux material irritating the esophagus, esophageal spasm, mental disorder, etc. General treatment and medication should be taken as prescribed by the doctor to relieve the symptoms. 1. Irritation of esophagus by reflux: When the amount of esophageal reflux increases, it may reflux and burn the chest, causing chest pain and tightness, leading to choking and blockage in the chest. Oral medication to inhibit gastric acid, such as ranitidine and omeprazole, should be taken as prescribed by the doctor. 2. Esophageal spasm: Prolonged esophageal reflux may directly induce esophageal spasm, leading to abnormalities in the nerves around the esophagus and blood circulation in the neck. At present, oral anticholinergic drugs, such as scopolamine, may be prescribed. 3. Mental disorders: If after the occurrence of esophageal reflux, the patient has long-term anxiety, nervousness or too much fear of the disease, which may affect normal eating, and there will be a sense of choking and blockage in the chest, the patient should follow the doctor’s instructions to take oral anti-anxiety drugs, such as meprobamate, butrospiracetam, and so on. Esophageal reflux caused by chest choking, may also be due to lying down after eating or due to gastrointestinal dysfunction, so it is recommended that the patient should consult a doctor in a timely manner, under the guidance of the doctor to choose the appropriate drug treatment.