Hand, foot and mouth vaccines can be given by different manufacturers. If they belong to the same type of vaccine product, only the vaccine manufacturers are different, then they can be mixed. The ingredients of HFMD vaccines produced by different manufacturers are the same, and the effect is also the same. Playing HFMD vaccines from different manufacturers will not cause any harm to the body, so you can play HFMD vaccines from different manufacturers. However, for better protection, try to choose vaccines from the same manufacturer for vaccination. When the supply of vaccine from the same manufacturer is insufficient or when vaccination needs to be given in a different place, you can choose a vaccine from a different manufacturer for vaccination. After vaccination, there may be adverse reactions such as redness, pain and fever at the vaccination site, so observe the vaccination site for half an hour before leaving. To find out whether it is possible to receive HFMD vaccine from a different manufacturer, consult a doctor at the hospital and let the doctor decide whether it is possible to receive the vaccine.