How the liver maintains a constant blood glucose concentration

The liver is the major organ for the storage, transport, and regulation of sugar in the body and plays an important role in maintaining constant blood glucose. The liver maintains a constant blood glucose concentration through the synthesis, catabolism, and gluconeogenesis of hepatic glycogen. When the blood glucose concentration increases, the body stores the excess glucose in the form of hepatic glycogen in the liver, and gluconeogenesis is diminished. When blood glucose drops, the liver releases hepatic glycogen into the blood again, and there is also a strengthening of gluconeogenesis, where the liver converts lactic acid, pyruvic acid, amino acids, glycerol, etc., into glucose and glycogen, so that the body’s blood glucose level is in a normal state. Normal fasting blood glucose range is 3.9-6.1mmol/L, and 2-hour postprandial blood glucose is less than 7.8mmol/L. The body regulates blood glucose through the liver to maintain blood glucose in a relatively stable state. People with abnormal blood glucose levels are advised to seek prompt medical attention.