There is no fastest treatment for lumbar spine compression nerve leg numbness, and standardized treatment is needed to relieve leg numbness, which can be treated with physical, medication and surgery. 1. Physical therapy: When the symptoms of herniated lumbar disc with numbness are mild, you can carry out physical therapy such as hot compresses and massages to alleviate the symptoms of numbness by relieving the tension of the muscles around the lumbar vertebrae. 2. Drug treatment: the numbness of lumbar intervertebral disc herniation patients is mainly related to the sensory abnormality caused by the nerve compression. Tizanidine can be applied to relax the muscles, reduce the degree of nerve compression, and vitamin B1 and other nutritious nerves, so as to alleviate the symptoms of numbness of the legs. 3. Surgery: When the symptoms of leg numbness are serious and the condition affects daily work and life, surgical treatment such as laminectomy is needed to relieve the pressure on the nerves, so as to achieve the effect of treating leg numbness. If you have been diagnosed with lumbar disc herniation, it is recommended that you undergo standardized treatment under the guidance of a doctor as soon as possible to reduce the adverse effects of the disease. All of the above drugs should be applied under the guidance of a physician, do not blindly use drugs on your own.