Whether it is good to take saxagliptin and dagliflozin together should be considered according to the patient’s level of glycemic control and the presence or absence of superimposed adverse effects. Saxagliptin can stimulate the secretion of insulin and inhibit the secretion of glucagon, and can enhance the utilization of glucose in peripheral tissues. It is used in the treatment of type 2 diabetes. Dagliflozin can exert a hypoglycemic effect by reducing the reabsorption of glucose by the kidneys and promoting the excretion of sugar from the urine, and is used to treat adult patients with type 2 diabetes mellitus to improve glycemic control on the basis of diet and exercise. If blood glucose levels are slightly elevated and can be controlled by a single drug, it is not a good idea to take the above 2 drugs together, which may lead to an increase in the incidence of adverse reactions; if blood glucose is high and cannot be controlled by a single drug, it is a good idea to take them together, which will lead to more effective control of blood glucose. Saxagliptin adverse reactions include nasopharyngitis, headache, gastrointestinal discomfort, allergic reactions and hypoglycemia. type 1 diabetes or diabetic ketoacidosis, moderate to severe hepatic and renal insufficiency patients are prohibited. Dagliflozin adverse reactions include hypotension, ketoacidosis, acute kidney injury and renal impairment, urinary sepsis and pyelonephritis, genital fungal infections, and bladder cancer. It is contraindicated in patients with a history of severe hypersensitivity reactions to the product, severe renal impairment, end-stage renal disease or patients requiring dialysis. Blood sugar should be checked to prevent hypoglycemia when applying the above two drugs.