Patients who take antihypertensive drugs with normal morning and high afternoon can adjust their blood pressure by increasing the frequency of drug use, adjusting the dosage of drugs, and combining drugs. 1. Increase the frequency of drug use: patients who take antihypertensive drugs with a normal morning and high afternoon may take short-acting antihypertensive drugs, such as captopril tablets, cotrimoxazole, etc. Such drugs have a short half-life and cannot control blood pressure in the normal range for a long time, so they need to be taken several times a day to increase the frequency of drug use. 2. Adjustment of dosage: many antihypertensive drugs are taken in small doses, and the dosage can be adjusted according to the blood pressure situation, such as amlodipine benzenesulfonate tablets with a starting dosage of 5mg, and the maximum dosage of 10mg, but it should be started after 7-14 days of medication, and the dosage should be adjusted under the guidance of the physician. 3. Combination of drugs: patients with high blood pressure is difficult to control, can be combined with drugs, according to the patient’s condition to choose two or three drugs, such as angiotensin-converting enzyme inhibitors and diuretics, or on the basis of the addition of β-blockers and other medication programs, in the use of medication, must follow the doctor’s instructions, the rational application of drugs, do not arbitrarily use the drug, to avoid causing serious adverse reactions.