Closed mouth is usually closed acne, this kind of acne is not painful and itchy, it will show tiny particles on the skin, there is something inside the closed mouth can be removed by topical medication, fruit acid, needle clearing and other methods. 1. Topical medication: When the skin has a closed mouth, you can consider applying topical medication with retinoic acid ingredients, such as adapalene gel and other medications. The medication can help to remove the over-keratinized epidermis, and dissolve the blockage of the closed mouth, so that the stuff inside can be removed. 2. Fruit acids: Apply weak acids on the skin, such as glycolic acid, supramolecular salicylic acid, etc., and neutralize them through the action of acidic substances on the skin, so as to exfoliate the clogged epidermis and make the occlusion open, so that the inside stuff can be discharged. 3. Needle clearing: you can go to the hospital or a regular medical institution for treatment, disinfection in the skin where there is a closed mouth, disinfection and then use a special acne needle to pick the epidermis, and then the inside of the things to remove. When the patient’s occlusion recurs, it is recommended to go to the hospital and under the guidance of the doctor for standardized treatment. All of the above removal methods need to be carried out under the guidance of a doctor.