Usually valsartan capsules do not damage the kidneys when taken for a long period of time, but for patients with renal artery stenosis or moderate to severe renal insufficiency, it may lead to an increase in blood creatinine, and may also lead to hyperkalemia, which needs to be used under the guidance of a doctor. Valsartan is commonly available in capsule and tablet form. The instructions for this product state that adverse reactions include mild transient headache, dizziness and dose-related upright hypotension, gastrointestinal discomfort. Rarely cough, diarrhea, fatigue, rhinitis, and rarely rash and angioneurotic edema. Rarely, hemoglobin and hematocrit are decreased. Because renal clearance of valsartan is only 30% of total plasma clearance, its administration is usually not renally damaging and no starting dose adjustment is required in patients with mild to moderate renal impairment. No dosing data are available for patients with severe renal impairment (creatinine clearance <30 ml/min). Valsartan reduces elevated blood pressure without affecting heart rate. It is used for the treatment of mild and moderate essential hypertension. The drug is contraindicated in people who are allergic to valsartan, pregnant. It is recommended that patients should standardize the use of medication under the guidance of a doctor, do not take it on their own, and when discomfort occurs, go to the hospital in time.