Bile reflux gastritis is mainly treated with medication, but it is difficult to be cured completely and easy to recur. Bile reflux gastritis can be under the guidance of the doctor to apply some enhancement of gastrointestinal dynamics of drugs, can promote gastric emptying, commonly used drugs are domperidone, cisapride, etc.; but also discretionary application of some gastric mucous membrane protective agent, can neutralize bile acid, such as bismuth potassium citrate, aluminum thiosulfate, etc.; can also be used to inhibit the secretion of gastric acid of drugs, such as lansoprazole, omeprazole and so on, to alleviate the clinical symptoms. After standardized treatment, the prognosis is generally good, but it is easier to recur and difficult to be cured completely. It is recommended that patients with bile reflux gastritis seek timely medical attention and active treatment.