If the 2-hour postprandial blood glucose is higher than the 1-hour blood glucose, and the retest is still higher than the normal value, it is necessary to control the diet, exercise, and use hypoglycemic drugs if necessary, and it is recommended to follow the doctor’s advice for treatment. If the 2-hour postprandial blood glucose is higher than the 1-hour postprandial blood glucose and is still higher than normal after retesting, then it is necessary to further clarify whether the diagnosis of hypoglycemia or diabetes mellitus can be made. After the diagnosis is clear, management can be carried out in the following aspects. 1. Provide diabetes health education to patients and learn self-management. 2. Formulate individualized diet plan and develop good eating habits. 3. Regular and appropriate exercise after meals according to one’s own situation, step by step, and long-term adherence. Blood glucose should be monitored before and after exercise to avoid excessive fluctuation of blood glucose. 4. Learn to monitor blood glucose, risk factors and complications. 5. When the blood glucose still can not reach the standard after exercise and diet therapy, you should apply hypoglycemic drug therapy under the guidance of doctor, such as oral metformin tablets, acarbose tablets, gliclazide delayed-release tablets, etc., and subcutaneous injection of insulin injections if necessary, and regular monitoring of blood glucose, and timely adjustment of medication. Diabetes mellitus is a common and frequent disease, a serious threat to human health, early detection and early treatment. We should advocate reasonable diet, regular exercise, improve lifestyle to delay and prevent the occurrence of diabetes. Seek medical attention when abnormal blood glucose levels are detected.