Generally speaking, cancer can be called clinically cured when there is no recurrence or metastasis within 5 years after treatment. Uroepithelial cancer can be said to be well when no recurrence is detected 20 years after treatment. Uroepithelial carcinoma is the most common pathological type of bladder cancer. It includes bladder cancer, ureteral cancer, renal pelvis cancer, etc. Hematuria is its common clinical manifestation, which is usually painless flesh-eye hematuria, the color is usually wash water-like, and some of them may have blood clots. Common treatment options include surgical treatment, bladder perfusion treatment, systemic chemotherapy, local radiotherapy, local intervention and so on. Despite the fact that uroepithelial carcinoma has not recurred for 20 years, it is still necessary to follow the physician’s advice for regular review and dynamic follow-up. The vigilance should not be relaxed in order to observe whether the tumor has recurrence and metastasis in time for timely treatment.