Polymorphic skin sarcoma generally refers to fibrosarcoma, epithelioid sarcoma and pleomorphic liposarcoma and other diseases, according to different diseases, the severity of pleomorphic skin sarcoma varies, and needs to be analyzed specifically. 1. Fibrosarcoma: it is a malignant tumor of fibroblasts, with slow growth, local invasive growth and recurrence, and metastasis only occurs in late stage. Fibrosarcoma occurs in the limbs and trunk, manifesting as deep, solitary limited hard nodules with tense surface. It is easy to recur after repeated excision, and can metastasize to the lungs, liver, etc. It is a more serious skin tumor. It is a kind of more serious skin tumor. 2. Epithelioid sarcoma: this disease is common in palms, forearms and lower limbs, manifested as papules, nodules and plaques. There are lymph node metastasis in early stage, and eventually it can be metastasized to lungs and pleura. The probability of recurrence after excision of skin lesions is high, and it is a more serious skin malignant tumor. 3. pleomorphic liposarcoma: pleomorphic liposarcoma usually occurs in the subcutaneous, skin lesions with clear boundary, is a kind of benign skin tumor, usually not serious. The severity of pleomorphic skin sarcoma needs to be analyzed according to the specific disease. It is recommended that patients go to the hospital in time to consult the doctor, and actively carry out the treatment after clarifying the cause of the disease to alleviate the condition. Follow the doctor’s instructions for regular checkups, and follow up with the doctor if you are not feeling well.